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The presence of abnormal joint flexibility and ocular symptoms related to lens subluxation suggests a connective tissue disorder. This combination of symptoms is characteristic of Marfan syndrome, which is known for its association with cardiovascular issues such as aortic aneurysms. Individuals with Marfan syndrome often exhibit hypermobility of joints and may develop ocular complications, particularly subluxation of the lens due to the altered structure of the connective tissues.

Aortic aneurysms are a common complication in patients with connective tissue disorders like Marfan syndrome, highlighting why the first choice in this scenario is appropriate. The structural weaknesses in connective tissues can lead to aortic dilation and subsequent aneurysm formation.

The other options do not typically present with the specific combination of symptoms mentioned. Ventricular septal defect and transposition of the great vessels predominantly relate to congenital heart anomalies and do not include the connective tissue symptoms described. DiGeorge syndrome is linked with immune deficiencies and specific facial features but does not generally present