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Which of the following is a criterion for diagnosing acute kidney injury (AKI)?

An increase in serum creatinine by 0.3 mg/dL within 48 hours

The criterion for diagnosing acute kidney injury (AKI) includes an increase in serum creatinine by 0.3 mg/dL within 48 hours. This specific threshold is part of the established guidelines for AKI, which also takes into account the time frame of the increase. The measurement of serum creatinine is essential as it reflects the kidney's ability to filter waste products from the blood. A noticeable increase in creatinine levels can indicate a deterioration in kidney function.

Options such as a decrease in urine output or changes in potassium levels can be associated with kidney injury, but they are not definitive criteria on their own for diagnosing AKI. Additionally, a decrease in baseline creatinine is not a recognized characteristic of AKI; AKI is defined by an increase, not a decrease, in creatinine levels. Thus, the increase in serum creatinine within the specified time frame remains a crucial clinical marker for diagnosing AKI.

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A decrease in urine output to less than 10 mL/hour

A decrease in baseline creatinine by 20%

An increase in potassium levels over 5 mEq/L

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