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The procedure involving intravenous drug administration is fundamentally characterized by its requirement for sterilization and adherence to proper technique. This is crucial because intravenous access directly introduces substances into the bloodstream, which can pose significant risks if not handled properly.

Sterilization ensures that the equipment, such as IV catheters and syringes, are free from pathogens that could lead to infection. Using aseptic techniques minimizes the risk of introducing bacteria and other micro-organisms into the patient's circulation, thereby preventing complications like sepsis or phlebitis.

Additionally, following the correct technique is important to ensure that the drug is delivered safely and effectively, as improper administration can lead to adverse events, including extravasation, incorrect dosing, or interruptions in medication delivery.

While it's true that intravenous procedures typically require trained personnel to ensure safety and efficacy, the highlighting factor here is the necessity of sterilization and technique. This protocol is vital in maintaining patient safety and ensuring the therapeutic efficacy of the drugs administered.